REJUBEAU EXO Skin Booster & Hair Booster 100% exosomes
100% Concentrated andPurified Exosome Boosterfor Skin and HairMore PowerfulMore PluripotentClear-Cut EffectUNDERSTANDING EXOSOMESExosomes might be tiny, but their role in the world of aesthetics is anything but small. These minuscule vesicles,ranging from 30 to 150 nanometers in size, are produced by various cells in our body and serve as essential messengersof communication. They carry powerful ingredients, including genetic material, proteins, and other molecules, andtravel throughout the body, delivering these precious cargoes to target cells.One of the interesting features of exosomes is their ability to transfer genetic material, particularly microRNAs, whichare like tiny conductors of a genetic orchestra. These microRNAs can tune up or down the expression of genes withinthe recipient cells, regulating their behavior and encouraging them to act in a more youthful and vibrant manner.According to studies, Exosomes may have the power to turn back the clock on aging cells, prompting them to behavelike they did when we were younger. This means they can boost collagen and elastin production, improve skin texture,reduce the appearance of wrinkles, and even promote hair growth.INTERCELLULAR COMMUNICATIONExosomes act as messengers in the intercellular communication network of the body. They are secreted by variouscell types, including stem cells, and are released into the extracellular environment. These exosomes carry a diversepayload of molecules, including microRNAs, mRNAs, proteins, and lipids. These molecular components are selectivelypackaged within the exosomes, allowing them to target specific cells and influence cellular behavior.CELLULAR UPTAKEUpon reaching the target tissue, exosomes interact with recipient cells by binding to their surface receptors. Thisinteraction facilitates the internalization of exosomes into the target cells, where the encapsulated bioactive moleculesare released and begin to exert their effectsGENETIC REGULATIONOne of the most significant contributions of exosomes in aesthetics is their ability to transfer genetic material,specifically microRNAs, to recipient cells. MicroRNAs are short, non-coding RNA molecules that play a vital rolein regulating gene expression. By delivering specific microRNAs to the target cells, exosomes can modulate theexpression of genes involved in cell growth, tissue repair, and collagen synthesis.STIMULATION OF CELL PROLIFERATION AND DIFFERENTIATIONExosomes promote the proliferation and differentiation of target cells, thereby encouraging tissue regeneration.For instance, in facial rejuvenation procedures, exosomes delivered into the skin can stimulate the proliferation offibroblasts. The fibroblast cells are responsible for producing collagen and elastin. This increase in collagen and elastinproduction leads to improved skin elasticity, reduced wrinkles, and an overall more youthful appearance.SUPPRESSION OF INFLAMMATIONInflammation is a common response to tissue damage or injury, but excessive or chronic inflammation can bedetrimental to the skin. Exosomes have demonstrated anti-inflammatory properties, which can help reduce skinredness, irritation, and swelling. By modulating the inflammatory response, exosomes promote a calmer and morebalanced environment in the treated tissues.COLLAGEN AND ELASTIN REMODELINGExosomes play a role in collagen and elastin remodeling, which is vital in maintaining skin structure and elasticity.Collagen and elastin production declines with age, causing the skin to sag and wrinkle. By boosting the synthesis offresh collagen and elastin fibers and their appropriate alignment within the skin matrix, exosomes can reverse thisprocess in its tracks.REJUBEAU EXO SB & HB 100%100% Concentrated and Purified Exosome Booster for Skin and HairCustomizing stem cells for intended purpose with priming factor iPSC (induced pluripotent stem cell)-derivedMSCs (mesenchymal stem cells) represent a type of stem cell that is generated by reprogramming umbilical cordblood into pluripotent stem cells and then differentiated into mesenchymal stem cells. It is called iMSC (inducedmesenchymal stem cell).Alleviate InflammationRelieve Dermatitis: skin spot / acne prone skin / problematic skinActivate skin cell and thicken dermis layerImprove skin elasticity, fine & deep wrinkles, sagging pores andrejuvenates skinRegenerate skin cell and antiagingPromote the proliferation of Elastin, Collagen, Hyaluronic AcidImprove skin tonePromote more radiant and young toned complexionSkin Booster 100 Stem Cell : 300 mg x 1 vialActivating Solution : 5 ml x 1 vialPROTOCOLGeneral Guidance1. Mix EXO SB 100% Exosome powder (300mg) with EXO SB 100% Activating solution (5ml).2. Cleanse the area to be treated thoroughly3. Apply the mixture to the skin and allow it to be absorbed thoroughly into the skin by MTS devicelike a Derma roller or a Derma pen.4. After the treatment, gently massage the residue to allow it to be absorbed into the skin and applycalming mask5. Apply calming and regenerating serum as a post-care.6. Number of treatment sessions:1) Intensive phase: 1 treatment a week for 5 weeks for skin.(It can be different depending on patient status)2) Maintenance phase: 1 treatment a month or if necessary▶ In case the blended solution causes any trouble to sensitive patients, the alternative guidance isrecommended.Full Hydration1. After mixing EXO’s Exosome powder (300mg) with EXO’s Activating solution (5ml), shake itsufficiently and leave it for 2 or 3 minutes for full hydration2. The mixed solution should be used within 3 hours and stored in a refrigerator.Alternative Guidance for Sensitive Skin1. Mix EXO’s Exosome powder (300mg) with Normal Saline (4 or 5 ml).2. Apply the mixed solution to the skin after treating with an MTS device like derma roller or Dermapen. After the treatment, the patient can use the EXO’s Activating solution (5ml) at home topically.Alternative Guidance [Japan only]1. Blend EXO’s Exosome powder (300mg) with Normal Saline (4 ml)2. Treat by using MTS Injector▶After the treatment, the patient can use the EXO’s Activating solution (5ml) at home topically.▶This guidance is suggested for the Japanese market only.Storage▶EXO’s Exosome powder should be stored in the refrigerator (2~6℃ )▶ Check the Exosome powder condition before hydration.White is normal. If the Exosome powder shows browning, do not use it and discard it.Hair Booster 100 Stem Cell : 300 mg x 1 vialActivating Solution : 5 ml x 1 vialSCALP-Hydrate and nourish the scalp-Promote a healthy hair growth cycle-Noticeably reduce hair loss-Visibly make hair look and feel soft, shiny, and fullPROTOCOLGeneral Guidance1. Mix EXO HB 100% Exosome powder (300mg) with EXO HB 100% Activating solution (5ml).2. Cleanse the area to be treated thoroughly.3. Apply the mixture to the scalp and allow it to be absorbed thoroughly into the skin by MTS devicelike a Derma roller or a Derma pen.4. After the treatment, gently massage the residue to allow it to be absorbed into the skin.5. Number of treatment sessions:1) Intensive phase: 1 treatment a week for 10 weeks for hair.(It can be different depending on patient status)2) Maintenance phase: 1 treatment a month or if necessary.▶ In case the blended solution causes any trouble to sensitive patients, the alternative guidance isrecommended.Full Hydration1. After mixing EXO’s Exosome powder (300mg) with EXO’s Activating solution (5ml), shake itsufficiently and leave it for 2 or 3 minutes for full hydration2. The mixed solution should be used within 3 hours and stored in a refrigerator.Alternative Guidance for Sensitive Skin1. Mix EXO’s Exosome powder (300mg) with Normal Saline (4 or 5 ml).2. Apply the mixed solution to the skin after treating with an MTS device like derma roller orDerma pen.▶After the treatment, the patient can use the EXO’s Activating solution (5ml) at home topically.Alternative Guidance [Japan only]1. Mix EXO’s Exosome powder (300mg) with Normal Saline (4 ml)2. Treat by using MTS Injector▶After the treatment, the patient can use the EXO’s Activating solution (5ml) at home topically.▶ This guidance is suggested for Japanese market only.StorageEXO’s Exosome powder should be stored in the refrigerator (2~6℃ )Check the Exosome powder condition before hydration. White is normal. If the Exosome powdershows browning, do not use it and discard it.
